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Cat No. | Product Name | Synonyms | Targets |
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T50079 | 2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine | Others | |
2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine can be used in the development of new deoxycytidine kinase (dCK) inhibitors. | |||
T6501 | Fludarabine Phosphate | NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl... | |||
T68917 | Fazarabine | ||
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is ph... | |||
T39114 | DI-82 | ||
DI-82 is a highly potent inhibitor of deoxycytidine kinase (dCK), displaying impressive biochemical activity with an IC50 value of 27.8 nM and a K i value of 9.2 nM. Additionally, DI-82 exhibits significant antitumor eff... | |||
T39550 | DI-87 | ||
DI-87 is a potent, orally active deoxycytidine kinase (dCK) inhibitor with high selectivity and an EC 50 of 10.2 nM. With demonstrated antitumor efficacy, DI-87 is employed in combination therapy specifically targeting t... | |||
T15378 | Gemcitabine elaidate | Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126 | Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy |
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracel... |
Cat No. | Product Name | Synonyms | Targets |
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T4731 | 2'-Deoxycytidine-5'-monophosphoric acid | dCMP,2'-Deoxycytidine 5'-monophosphate | Others , Endogenous Metabolite |
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation t... | |||
T4972 | 2'-Deoxycytidine-5'-diphosphate trisodium | dCDP | Endogenous Metabolite |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. |
Cat No. | Product Name | Species | Expression System |
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TMPJ-00922 | DCK Protein, Human, Recombinant (His & T7) | Human | E. coli |
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanos... |