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Search Results for " deoxycytidine kinase "

Targets

6

Compounds

2

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T50079 2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine Others
2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine can be used in the development of new deoxycytidine kinase (dCK) inhibitors.
T6501 Fludarabine Phosphate NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl...
T68917 Fazarabine
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is ph...
T39114 DI-82
DI-82 is a highly potent inhibitor of deoxycytidine kinase (dCK), displaying impressive biochemical activity with an IC50 value of 27.8 nM and a K i value of 9.2 nM. Additionally, DI-82 exhibits significant antitumor eff...
T39550 DI-87
DI-87 is a potent, orally active deoxycytidine kinase (dCK) inhibitor with high selectivity and an EC 50 of 10.2 nM. With demonstrated antitumor efficacy, DI-87 is employed in combination therapy specifically targeting t...
T15378 Gemcitabine elaidate Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126 Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracel...
Cat No. Product Name Synonyms Targets
T4731 2'-Deoxycytidine-5'-monophosphoric acid dCMP,2'-Deoxycytidine 5'-monophosphate Others , Endogenous Metabolite
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation t...
T4972 2'-Deoxycytidine-5'-diphosphate trisodium dCDP Endogenous Metabolite
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00922 DCK Protein, Human, Recombinant (His & T7) Human E. coli
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanos...
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